Leaching of plasticizers from temporary denture soft lining materials

Munksgaard, EC

HERO ID

789530

Reference Type

Journal Article

Year

2004

Language

English

PMID

14871201

HERO ID 789530
In Press No
Year 2004
Title Leaching of plasticizers from temporary denture soft lining materials
Authors Munksgaard, EC
Journal European Journal of Oral Sciences
Volume 112
Issue 1
Page Numbers 101-104
Abstract The loss of the plasticizers dibutylphthalate, butylphthalylbutyl glycolate, benzylbenzoate, methylsalicylate, and benzylsalicylate from four soft lining materials was measured. A 0.1% aqueous solution of triton X-100, reduced was used as immersion medium, since the solubility of plasticizer in this medium was close to that of saliva. The loss of plasticizer was monitored up to 30 d after mixing. For two of the materials, the average amount of leached dibutylphthalate within the first day exceeded the proposed tolerable daily intake (TDI) by about 11 and 32 times, respectively, for an average adult person. Similarly, for these two materials, the average daily amount within the first 30 d of leached dibutylphthalate was 2.2 and 6.6 times larger, respectively, than the TDI limit. The cumulative amount leached over 30 d for each of the four materials was 128-253 mg plasticizer g(-1). The results indicate the need for further biological evaluations of these products.
Doi 10.1111/j.0909-8836.2004.00091.x
Pmid 14871201
Wosid WOS:000188864400017
Url https://search.proquest.com/docview/80148967?accountid=171501
Is Certified Translation No
Dupe Override No
Comments Source: Web of Science WOS:000188864400017
Is Public Yes
Language Text English
Keyword Adult; Benzoates/chemistry/toxicity; Dental Restoration, Temporary; Denture Liners; Denture, Complete; Humans; Linear Models; Materials Testing; Maximum Tolerated Dose; Octoxynol; Phthalic Acids/chemistry/toxicity; Plasticizers/ chemistry/ toxicity; Salicylates/chemistry/toxicity; Saliva, Artificial
Is Qa No