Transcriptome analysis of O3-exposed Arabidopsis reveals that multiple signal pathways act mutually antagonistically to induce gene expression

Tamaoki, M; Nakajima, N; Kubo, A; Aono, M; Matsuyama, T; Saji, H

HERO ID

80053

Reference Type

Journal Article

Year

2003

Language

English

PMID

15010611

HERO ID 80053
In Press No
Year 2003
Title Transcriptome analysis of O3-exposed Arabidopsis reveals that multiple signal pathways act mutually antagonistically to induce gene expression
Authors Tamaoki, M; Nakajima, N; Kubo, A; Aono, M; Matsuyama, T; Saji, H
Journal Plant Molecular Biology
Volume 53
Issue 4
Page Numbers 443-456
Abstract To analyze cellular responses to ozone (O3), we performed a large-scale analysis of the Arabidopsis transcriptome after plants were exposed to O3 for 12 h. By using cDNA macroarray technology, we identified 205 non-redundant expressed sequence tags (ESTs) that were regulated by O3. Of these, 157 were induced and 48 were suppressed by O3. A substantial proportion of these ESTs had predicted functions in cell rescue/defense processes. Using these isolated ESTs, we also undertook a comprehensive investigation of how three hormones, ethylene (ET), jasmonic acid (JA), and salicylic acid (SA), interact to regulate O3-induced genes in various genetic backgrounds of Arabidopsis, such as the ET-insensitive ein2-1, JA-resistant jar1-1, and SA-insensitive npr1-1. The expression of half of the 157 induced genes, especially cell rescue/defense genes, was controlled by ET and JA signaling, indicating that O3-induced defense gene expression at this stage was mainly regulated by ET and JA. Clustering analysis of the 157 O3-induced gene expressions revealed that multiple signal pathways act mutually antagonistically to induce the expression of these genes, and many cell rescue/defense genes induced by ET and JA signal pathways were suppressed by SA signaling, suggesting that the SA pathway acts as a strong antagonist to gene expression induced by ET and JA signaling.
Doi 10.1023/B:PLAN.0000019064.55734.52
Pmid 15010611
Wosid WOS:000220093600002
Url http://link.springer.com/10.1023/B:PLAN.0000019064.55734.52
Is Certified Translation No
Dupe Override No
Comments ECRIB. 3 in O3 is a subscript.Plant Mol. Biol. 53: 443-456.
Is Public Yes
Language Text English
Keyword Arabidopsis thaliana; ethylene; jasmonic acid; macroarray; ozone; salicylic acid; subset macroarray
Is Qa No