The relationship between blood lead, bone lead and child intelligence

Wasserman, GA; Factor-Litvak, P; Liu, X; Todd, AC; Kline, JK; Slavkovich, V; Popovac, D; Graziano, JH

HERO ID

81451

Reference Type

Journal Article

Year

2003

Language

English

PMID

12815520

HERO ID 81451
In Press No
Year 2003
Title The relationship between blood lead, bone lead and child intelligence
Authors Wasserman, GA; Factor-Litvak, P; Liu, X; Todd, AC; Kline, JK; Slavkovich, V; Popovac, D; Graziano, JH
Journal Child Neuropsychology
Volume 9
Issue 1
Page Numbers 22-34
Abstract We report associations between serial measures of blood lead and intelligence in children age 10–12 years, half heavily exposed to lead from the prenatal period onward, and half relatively unexposed. For a subsample, we examine bone lead-IQ associations, comparing them with blood lead associations. Both blood and bone lead levels were associated with intelligence decrements, small relative to the contribution of social factors. For each doubling of Tib-Pb, Full Scale, Performance, and Verbal IQ decreased by an estimated 5.5, 6.2, and 4.1 points, respectively. Bone lead-IQ associations were stronger than those for blood lead, which nonetheless provide robust analogues. Current BPb, easy to obtain, provides a useful means for assessing Pb exposure/IQ associations.
Doi 10.1076/chin.9.1.22.14497
Pmid 12815520
Wosid WOS:000183977700003
Url https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037482127&doi=10.1076%2fchin.9.1.22.14497&partnerID=40&md5=9e207dbb4baa00db9c52ba05318722d6
Is Certified Translation No
Dupe Override No
Comments ECRIB.Child Neuropsychol. 9: 22-34.
Is Public Yes
Language Text English
Is Qa No