Anti-oxidative, anti-inflammatory and whitening effects of phenolic compounds from Bambusae Caulis in Liquamen
Park, KH; Lee, MW
| HERO ID | 865573 |
|---|---|
| In Press | No |
| Year | 2012 |
| Title | Anti-oxidative, anti-inflammatory and whitening effects of phenolic compounds from Bambusae Caulis in Liquamen |
| Authors | Park, KH; Lee, MW |
| Journal | Natural Product Research |
| Volume | 26 |
| Issue | 18 |
| Page Numbers | 1687-1691 |
| Abstract | Bambusae Caulis in Liquamen (BCL) is the distilled product of the condensation from the burning of Phyllostachys nigra var. henosis (Gramineae). The activity-guided isolation of BCL yielded four phenolic compounds: 2,6-dimethoxyphenol (1), 1,2-dihydroxybenzene (2), 1,3-dihydroxybenzene (3) and 1,2-dibenzenecarboxylic acid (4). We evaluated the anti-oxidative, anti-inflammatory and whitening effects of these compounds, via assays, of 1,1-diphenyl-2-picrylhydazyl (DPPH) radical scavenging activity and inhibition of nitric oxide (NO) production in lipopolysaccharide-stimulated RAW 264.7 macrophage cells as well as inhibition of tyrosinase activity and melanin production in B16F10 melanoma cells. The results showed that 2 and 3 exhibited significant DPPH radical scavenging activity as well as inhibitory effects on NO production, tyrosinase activity and melanin production. These results suggested that BCL and compounds 2 and 3 can be developed as anti-oxidative, anti-inflammatory and whitening ingredients. |
| Doi | 10.1080/14786419.2011.593517 |
| Pmid | 21985061 |
| Wosid | WOS:000307927400005 |
| Is Certified Translation | No |
| Dupe Override | No |
| Is Public | Yes |
| Language Text | English |
| Keyword | Bambusae Caulis in Liquamen; 1,1-diphenyl-2-picrylhydazyl radical; nitric oxide; tyrosinase; melanin |
| Is Qa | No |