Chemical alternatives assessment: enabling substitution to safer chemicals

Lavoie, ET; Heine, LG; Holder, H; Rossi, MS; Lee, RE; Connor, EA; Vrabel, MA; Difiore, DM; Davies, CL

HERO ID

1011316

Reference Type

Journal Article

Year

2010

Language

English

PMID

21062050

HERO ID 1011316
In Press No
Year 2010
Title Chemical alternatives assessment: enabling substitution to safer chemicals
Authors Lavoie, ET; Heine, LG; Holder, H; Rossi, MS; Lee, RE; Connor, EA; Vrabel, MA; Difiore, DM; Davies, CL
Journal Environmental Science & Technology
Volume 44
Issue 24
Page Numbers 9244-9249
Abstract The pace of substituting away from chemicals of concern is accelerating. Industry,NGOs,andgovernments are all playing roles in identifying safer alternatives. Substitution that is not informed by the best available information and science can lead to unintended and undesired consequences. Alternative chemicals might have human health andenvironmental profiles that are similar to those of the chemicals of concern or that are different but pose concern for other end points. Uninformed decisions may cause industry to incur costs repeatedly in moving from one alternative to another. CAAs are a proven tool for informing substitution to safer alternatives and minimizing the likelihood of unintended consequences. Their track record has made them a risk managementoption under EPA's existing chemical action plans.CAAs are in progress for BPA in thermal paper and the flame retardant decaBDE. Even when a CAA does not identify an optimal alternative, the tool proves valuable in clarifying the state of the scien eamongpotential alternatives and pointing to the need for chemical research andinnovation: effectively posing a focused green chemistry challenge. The DfE CAA methodology outlined here provides a strong foundation for comparing alternatives and informing substitution to safer chemicals in a wide range of industries and applications and may serve as a critical tool for guiding chemical risk management and innovation in the future. © 2010 American Chemical Society.
Doi 10.1021/es1015789
Pmid 21062050
Url https://www.scopus.com/inward/record.uri?eid=2-s2.0-78650264423&doi=10.1021%2fes1015789&partnerID=40&md5=95df590ce130434b4eedc483cd94e8ad
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Language Text English
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